PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▲ |
---|---|---|---|---|---|---|---|
Clostridium perfringens | Delta toxin | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Vibrio cholerae | Unknown | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Clostridium perfringens | Unknown | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Clostridium tetani | Unknown | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Clostridium botulinum | Unknown | GM2(NeuAc) | Monosialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Escherichia coli | SfaA | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
Escherichia coli | S-fimbriae | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
Bordetella pertussis | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
Influenza virus | Unknown | Neuraminic acid-containing sialoglycoproteins | Glycoproteins | Binding | 15973004 | ||
Mycoplasma pneumoniae | Unknown | GSLs containing terminal Gal(3SO4)β1-residues | Glycosphingolipids | Binding | 15973004 | ||
Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 15973004 |
Pseudomonas aeruginosa | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Cystic fibrosis patients | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 |
Escherichia coli | SfaA | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 15973004 | |
Escherichia coli | S-fimbriae | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 15973004 | |
Escherichia coli | F1C | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 15973004 | |
Escherichia coli | P-fimbriae | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Bordetella pertussis | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group Lewis b (Leb) antigen | Oligosaccharides | Binding | 15973004 | ||
Escherichia coli | S-fimbriae | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
Escherichia coli | SfaS | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
Clostridium tetani | Tetanus neurotoxin | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Clostridium botulinum | Neurotoxin (type A/B) | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Clostridium tetani | Unknown | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Clostridium botulinum | Unknown | GD2 | Disialoglycosphingolipids | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 | |
Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialyl-dimeric Lewis x (SdiLex) (GSL) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 15973004 |
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Last updated: August 19, 2024