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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Haemophilus influenzae | Hia | unknown carbohydrate ligand | Saccharides | Human conjunctival cells (respiratory tract) | Binding | 10341176 | |
| Actinomyces odontolyticus | Unknown | unknown carbohydrate ligand | Saccharides | Tongue | Binding | 9712794 | |
| Streptococcus pneumoniae | PclA (pneumococcal collagen-like protein A) | unknown carbohydrate ligand | Saccharides | Detroit 562/A549 cell lines | Binding | 18557785 | |
| Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
| Anaplasma marginale | "MSP1a, MSP1b, MSP2" | unknown carbohydrate ligand | Saccharides | Binding | 16299269 | ||
| Escherichia coli | Type 1-fimbriae | trisaccharide: Man(a1-3)Man(b1-4)GlcNAc | Oligosaccharides | Patient with urinary tract infection | Man(a1-3)Man(b1-4)GlcNAc | Binding | 6138149 |
| Escherichia coli | Type 1-fimbriae | trisaccharide: Man(a1-3)Man(b1-4)GlcNAc | Oligosaccharides | Man(a1-3)Man(b1-4)GlcNAc | Binding | 16564136 | |
| Bordetella pertussis | Adhesins | terminal Gal(3SO4) β1- residues | Sulfoglycosphingolipids | Human lung, Human trachea | Gal(3SO4)(b | Binding | 1918002 |
| Bordetella parapertussis | Adhesins | terminal Gal(3SO4) β1- residues | Sulfoglycosphingolipids | Gal(3SO4)(b | Binding | 1918002 | |
| Lactobacillus johnsonii | Unknown | nLc6 (Neolactohexaosylceramide) | Oligoglycosylceramides | Rabbit thymus | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Escherichia coli | K88ab/K88ac/K88ad | nLc6 (Neolactohexaosylceramide) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Cytomegalovirus | Unknown | nLc6 (Neolactohexaosylceramide) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | nLc6 (Neolactohexaosylceramide) | Oligoglycosylceramides | Rabbit thymus, Human erythrocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine-activated cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12640357 |
| Streptococcus pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Chinchilla tracheal epithelium | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10090858 |
| Neisseria gonorrhoeae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Streptococcus pneumoniae | CbpA; SpsA; PbcA; PspC (CBPs) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine activated epithelial and endothelial cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10341176 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human skin | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Actinomyces viscosus | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Lactobacillus johnsonii | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human erythrocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Human granulocytes | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9228091 |
| Lactobacillus casei | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Intestinal tract | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8912650 |
| Actinomyces naeslundii | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Dog small intestine | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Escherichia coli | K88ab/K88ac/K88ad | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 |
