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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▲ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Bordetella pertussis | CRD (carbohydrate recognition domain) of Fha (Filamentous Hemagglutinin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Respiratory ciliated cells, Alveolar macrophages | Gal(b1-4)Glc(b1-1)Cer | Binding | 8514379 |
| Bordetella pertussis | Pertussis toxin | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
| Bordetella pertussis | FHA (1141-1279) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Ciliated epithelium of the respiratory tract | Gal(b1-4)Glc(b1-1)Cer | Binding | 11348687 |
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human cilia of the respiratory epithelium | Gal(b1-4)Glc(b1-1)Cer | Binding | 1729677 |
| Bordetella pertussis | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human lung, Human trachea | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 1918002 |
| Bordetella pertussis | FimD | VLA-5 (very late activation antigen 5) | Glycoproteins | Monocytes | Binding | 11348687 | |
| Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
| Bordetella pertussis | Pertussis toxin | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Bordetella pertussis | PT (subunit S2 of B oligomer) | Haptoglobin | Glycoproteins | Binding | 1729677 | ||
| Borrelia afzelii | Unknown | Dermatan sulfate | Glycosaminoglycans | Glial cells | Binding | 10085013 | |
| Borrelia afzelii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia afzelii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia afzelii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia afzelii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
| Borrelia burgdorferi | BBK32 | Dermatan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 16368999 | |
| Borrelia burgdorferi | Unknown | Dermatan sulfate | Glycosaminoglycans | Glial cells | Binding | 10085013 | |
| Borrelia burgdorferi | BBK32 | Heparin | Glycosaminoglycans | Mammalian cell surface | Binding | 16368999 | |
| Borrelia burgdorferi | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7622201 | |
| Borrelia burgdorferi | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Borrelia burgdorferi | Unknown | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7622201 | |
| Borrelia burgdorferi | Unknown | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 |
