Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species ▼ | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Streptococcus pneumoniae | FcsSBP (fucose solute-binding protein) | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 19285508 | |
| Streptococcus pneumoniae | FcsSBP (fucose solute-binding protein) | Blood group A antigen | Oligosaccharides | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc | Binding | 19285508 | |
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | C3 and complement factor H | Glycoproteins | Binding | 12640357 | ||
| Streptococcus pneumoniae | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Type-II lung cells, Vascular endothelial cells | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7752878 |
| Streptococcus pneumoniae | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Chinchilla tracheal epithelium | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10090858 |
| Streptococcus pneumoniae | PsaA (Lary family) | unknown carbohydrate ligand | Saccharides | Nasopharynx, Alveolar epithelial cells | Binding | 10341176 | |
| Streptococcus pneumoniae | PclA (pneumococcal collagen-like protein A) | unknown carbohydrate ligand | Saccharides | Detroit 562/A549 cell lines | Binding | 18557785 | |
| Streptococcus pneumoniae | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3413084 | |
| Streptococcus pneumoniae | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Streptococcus pneumoniae | SpsA | IgA | Glycoproteins | Binding | 10341176 | ||
| Streptococcus pneumoniae | PspC (Lary family) (alias: SpsA/CbpA/PbcA/Hic) | IgA | Glycoproteins | Binding | 12640357 | ||
| Streptococcus parasanguinis | FimA (Lary family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus parasanguinis | FimA (Lral family); localized to the tip of peritrichous surface fimbria | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | Pac (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Saliva | Binding | 12640357 | |
| Streptococcus mutans | Pac (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | Ag I/II (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | Unknown | Salivary glycoprotein (gp340) | Glycoproteins | Dental plaque (caries-associated) | Binding | 11007786 | |
| Streptococcus mitis | S-fimbriae | unnamed ligand | Oligosaccharides | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 2885220 | |
| Streptococcus gordonii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins in the presence of sialic acid | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Collagen (type I) | Glycoproteins | humHn oral cavity (root dentine) | Binding | 16177339 | |
| Streptococcus gordonii | SspA/SspB (AgI/II family) | Salivary glycoprotein (gp340) | Glycoproteins | Human oral cavity (in fluid and surface-associated phases) | Binding | 16177339 |
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Partly supported by NIH Common Fund Grant #1U01GM125267-01
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