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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Escherichia coli | K88ab/K88ac/K88ad | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11953368 | |
| Propionibacterium granulosum | Unknown | Lewis x (Lex) (GSL) | Oligoglycosylceramides | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2435422 | |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | DSPG (Disialosyl paragloboside) | Disialoglycosphingolipids | Human erythrocytes | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Shigella dysenteriae | B subunit | DSGG (Disialosyl galactosyl globoside, disialyl Gb5) | Disialoglycosphingolipids | Human erythrocytes | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sialyl Lewis a (SLea) (GSL) | Monosialoglycosphingolipids | Human bile bladder tumor | NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Actinomyces viscosus | Unknown | unnamed ligand | Sialoglycosphingolipids | Frog brain | Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Borrelia burgdorferi | Unknown | Chondroitin 4-sulfate (C-4S) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Actinomyces viscosus | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog intestine | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Actinomyces naeslundii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | PrsG (class III) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9673272 |
| Escherichia coli | P-fimbriae | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9673272 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes, Rabbit intestine | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | F1C | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse feces | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Vero cells | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Various sources | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Various sources | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Mycoplasma pneumoniae | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Mycoplasma pneumoniae | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human colon adenocarcinoma cells (WiDr ) | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2470753 |
| Lactobacillus johnsonii | Unknown | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Shigella dysenteriae | B subunit | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Shigella dysenteriae | B subunit | SSEA-3 (GSL) (Galactosyl globoside; Gb5) | Oligoglycosylceramides | Human kidney | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
