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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Borrelia burgdorferi | "OspA, OspB, OspC" | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 16299269 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 9712817 | |
| Helicobacter canis | Lectin-hemagglutinin adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Escherichia coli | F1C | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | K88ad | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 11953368 | |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 | |
| Pseudomonas aeruginosa | Exoenzyme S | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 1679039 | |
| Escherichia coli | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 2435422 | |
| Borrelia burgdorferi | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 7622201 | |
| Borrelia burgdorferi | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Shigella dysenteriae | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 12628483 | |
| Propionibacterium freudenreichii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Propionibacterium granulosum | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Actinobacillus pleuropneumoniae | LPS | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Binding | 10496867 | |
| Escherichia coli | F1C | Gb2 (Galabiosylceramide) | Diosylceramides | Synthetic | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Gb2 (Galabiosylceramide) | Diosylceramides | Gonorrhoeae patients | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2468365 |
| Actinomyces viscosus | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Human meconium | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces viscosus | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Dog intestine | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Actinomyces naeslundii | Unknown | Gb2 (Galabiosylceramide) | Diosylceramides | Human meconium | Gal(a1-4)Gal(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Human erythrocytes | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Vibrio cholerae | Cholera toxin | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Vibrio cholerae | Unknown | Lactosylceramide (Lactocerebroside) | Diosylceramides | Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 |
