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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Bordetella pertussis | Pertactin | unknown carbohydrate ligand | Saccharides | Eukaryotic cells | Binding | 11348687 | |
| Enterococcus faecalis | EfaA (Lary family) | D-Galactose-containing residues | Saccharides | Gal | Binding | 12640357 | |
| Anaplasma marginale | "MSP1a, MSP1b, MSP2" | unknown carbohydrate ligand | Saccharides | Binding | 16299269 | ||
| Borrelia burgdorferi | DbpA | Decorin | Proteoglycans | Extracellular matrix (ECM) | Binding | 12761224 | |
| Influenza virus | Unknown | Endothelial cell-specific molecule (ESM) | Proteoglycans | Not Binding | 1740131 | ||
| Borrelia burgdorferi | "DbpA, DbpB, Bgp" | Decorin | Proteoglycans | Binding | 16299269 | ||
| Neisseria meningitidis | OpcA | Sialic acid-containing polysaccharides | Polysaccharides | Epithelial cells | Binding | 18076035 | |
| Bordetella pertussis | FHA (442-863) | Dextran sulfate | Polysaccharides | WiDr cells, HeLa cells, Vero cells, Extracellular matrix (ECM) | Binding | 11348687 | |
| Human immunodeficiency virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human T cells | Binding | 9420059 | |
| Human immunodeficiency virus | Unknown | Dextran sulfate | Polysaccharides | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | Pentosan polysulfate (PP) | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | Dextran sulfate | Polysaccharides | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | Dextran sulfate | Polysaccharides | Human cervical cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | Pentosan polysulfate (PP) | Polysaccharides | Human epithelial cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | Dextran sulfate | Polysaccharides | Human epithelial cells | Binding | 9420059 | |
| Plasmodium falciparum | Unknown | Polylactosamine of band 3 | Polysaccharides | Binding | 8574698 | ||
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Dextran sulfate | Polysaccharides | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Actinomyces naeslundii | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Actinomyces viscosus | Unknown | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Shigella dysenteriae | B subunit | unnamed ligand | Polyglycosylceramides | Rat small intestine | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 3543013 |
| Shigella dysenteriae | Shiga toxin | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 2435422 | |
| Escherichia coli | Unknown | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Binding | 2435422 | |
| Shigella dysenteriae | Unknown | unnamed ligand | Polyglycosylceramides | GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 | Not Binding | 2435422 | |
| Escherichia coli | S-fimbriae | unnamed ligand | Oligosaccharides | Neural cell lines | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 16564136 |
