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MIRAGE
Signaling by PDGF

Summary
Species
Caenorhabditis elegans
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PDGF precursor dimers (AA, BB, A/B, CC, DD)PDGF precursor dimers (AA, BB, A/B, CC, DD)proPDGF-AA dimerpvf-1active PDGF-AA dimerproPDGF-BB dimeractive PDGF-BB dimerpvf-1proPDGF-AB dimerPDGF A/B heterodimerNovel PDGF precursor dimers (CC, DD)Novel PDGF precursor dimers (CC, DD)pvf-1Active PDGF dimers (CC, DD)Extracellular matrix ligandsPDGF A and B chains:ECM complexpvf-1PDGFRA, PDGFRBPDGF:PDGF receptor dimerActive PDGF dimers (AA, AB, BB)ATPADPPDGF beta receptor:PDGF chain B homodimerPhospho PDGF beta receptor: PDGF chain B homodimerPDGF alpha receptor: PDGF dimersPhospho PDGF alpha receptor:PDGF dimersPDGF alpha/beta:PDGF AB and BB dimersPhospho PDGF alpha-beta dimer:PDGF AB or BB dimerstype I PDGFR-binding tyrosine kinase inhibitorsPDGFR:type I PDGFR-binding TKIstype II PDGFR-binding tyrosine kinase inhibitorsPDGFR:type II PDGFR-binding TKIs
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025