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MIRAGE
Integrin signaling

Summary
Species
Caenorhabditis elegans
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GTPRAP1:GTPRAP1:GDPGDPPIP2Rap1-GTP:PIP2:RIAMmig-10TLN1Talin:RIAM complexIntegrin alphaIIb beta3:p-Y530-SRC:CSKIntegrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complexFocal complexIntegrin binding divalent cationsQ18096Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK)CSKTalin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC)Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC)Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC)ATPADPTalin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2PTK2Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2Integrin alpha2bbeta3Integrin alpha IIb p(T779)-beta 3Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHCIntegrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHCTalin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYKSYKTalin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P34446 Integrin alpha pat-2
  • pat-2
 view
Q27874 Integrin beta pat-3
  • pat-3
 view
Q9GYK2 Uncharacterized integrin beta-like protein C05D9.3
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025