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MIRAGE
Degradation of the extracellular matrix

Summary
Species
Canis familiaris
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
BSGBSG:MMP1(100-469)A0A8I3RPH1ElastinCleaved elastinFibrillin 1,2,(3)Cleaved fibrillin 1,2,(3)Fibrillin-1Cleaved fibrillin-1Fibronectin matrixCleaved fibronectin matrixCleaved fibronectin matrix Ala(271)/Val(272)NID1NID1NID1ACANACANH2OACANBCANBCANBCANBCANBCANDCNDCNDCNCDH1(155-882):Ca2+ dimerE-cadherin strand dimer fragment 701-882E-cadherin strand dimer fragment 155-700MMP1, 3, 13, (2, 7-12, 19)Alpha 2-macroglobulin:MMP1, 3, 13, (2, 7-12, 19)A2M tetramerMMP2, MMP7, MMP9CD44:MMP2, MMP7, MMP9CD44SPP1SPP1SPP1substrate protein for calpainscalpain-cleaved proteinOPTCOPTCOPTCOPTCOPTCOPTCOPTCSCUBE3SCUBE3SCUBE3SCUBE1,SCUBE3SCUBE1,SCUBE3 polymer, SCUBE3 polymer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
A0A8I3P533 ADAM metallopeptidase with thrombospondin type 1 motif 5
  • ADAMTS5
 view
F1PAA9 Cadherin-1
  • CDH1
 view
Q29393 Decorin
  • DCN
  • DCN1C
 view
Q6Y4Q5 Stromelysin-1
  • MMP3
 view
Q9GL24 Procathepsin L
  • CTSL
  • CTSL1
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025