Negative regulation of MET activity

Summary
Species
Canis familiaris
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimerPiHGF:p-Y1234,Y1235,Y1356-MET dimerH2OHGF:p-Y,1349,Y1356-MET dimerHGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer)HGF:p-4Y-MET dimer:GRB2:CBL,(HGF:p-Y1003,4Y-MET dimer:CBL)CBL:GRB2,CBLATPHGF:p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:p-Y1003,4Y-MET dimer:p-Y-CBL)ADPHGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL)UbHGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillinCIN85:endophilinLRIG1MET:LRIG1METMET:Ub-LRIG1HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1)HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM)EPS15:HGS:STAM
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying 1 entry
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q867B7 Hepatocyte growth factor
  • HGF
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025