Downregulation of SMAD2/3:SMAD4 transcriptional activity

Summary
Species
Drosophila melanogaster
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p-2S-SMAD2,3:SMAD4p-2S-SMAD2,3:SMAD4:SKI/SKIL:NCORSmrSKIMedMedUb-SMAD4:USP9XfafH2OMedUbNedd4p-T-2S-SMAD2,3:SMAD4:NEDDL4p-T,2S-SMAD2,3:SMAD4Ub-p-T-2S-SMAD2,3:SMAD4UbSmurfp-T-2S-SMAD2,3:SMAD4:SMURF2MedO96660Bx42ATP1B4:SNW1Homologues of ATP1B4HDAC1p-2S-SMAD2/3:SMAD4:TGIF:HDAC1TGIFp-2S-SMAD2,3:SMAD4:PARP1PARP1NADNAMPAR-SMAD2,3:PAR-SMAD4p-2S-SMAD2,3:SMAD4:PPM1AalphSmoxH2OPiSmoxADPO96660ATPUb-SKI/Ub-SKIL
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025