RET signaling

Summary
Species
Gallus gallus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GFRA1,GFRA3RET:GFRA1,GFRA3RETGFRA1, GFRA2RET:GFRA1,GFRA2GFRA4RET:GFRA4RET:GFRA1,GFRA2:GDNF,NRTNGDNF,NRTNARTNRET:GFRA1,GFRA3:ARTNRET:GFRA:GDNF complexes2x RET:GFRA:GDNF complexesATPADP2x p-5Y-RET:GDNF:GFRA complexesDOK1,DOK2,DOK4,DOK5,DOK62x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6RET interactors2x p-5Y-RET:GDNF:GFRA complexes:RET interactors2x p-5Y-RET:GDNF:GFRA complexes:FRS2FRS22x p-5Y-RET:GDNF:GFRA complexes:SHC1SHC12x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC12x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1GRB2-1:SOS12x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1GRB22x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1p-5Y-RET:GDNF:GFRA complexes with and without p-SHC12x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2GAB1,GAB22x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB22x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ksp85-containing Class 1A PI3KsPTPN112x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11GRB102x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB102x p-5Y-RET:GDNF:GFRA complexes:PLCG1PLCG12x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAPSRC-1, RAP1GAP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying 1 entry
UniProt ID Protein Name Gene Symbol Pathway Viewer
O13156 GDNF family receptor alpha-1
  • GDNFRA
  • GFRA1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025