ISG15 antiviral mechanism

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p-IRF3 dimer:PIN1PIN1ISG15ISG15:NEDD4NEDD4ATPPPiISG15:UBA7AMPUBA7UBCH8ISG15:UBCH8ISG15 E3 ligasesISG15:UBCH8:ISG15 E3 ligaseISGylated 4EHP4EHPEIF4FeIF4F:mRNAISGylated 4EHP:mRNAPPM1BISGylated PP2CBISGylated Filamin BFLNBISG15 targetsISGylated host proteinsISGylated IRF3IRF3NS1 dimerISGylated NS1N-myristoyl GAG (P12493) proteinmonoubiquitinated N-myristoyl GAG (P12493) proteinUbpolypeptideNS1 homodimer:ImportinImportinISGylated E2 conjugating enzymesE2 congugating enzymes
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025