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MIRAGE
Apoptosis induced DNA fragmentation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
DFFA:DFFBDFF:associated with the importin-alpha:importin-beta complexKPNA1:KPNAB1DFF:associated with the importin-alpha:importin-beta compleximportin-alpha:importin-beta complexDFFA:DFFBCaspase cleaved DFFA (117)caspase-3-cleaved DFFA (117,224):DFFB complexDFFA(225-331)DFFA(1-117)DFFA(118-224)DFFBDFF40 homodimer/homooligomerDFF40 associated with chromatinHistone H1 bound chromatin DNAHMGB1/HMGB2HMGB1/HMGB2- bound chromatinDNADFF cleaved DNADFFBDFFACaspase-3active caspase-3DFF40 homodimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P09429 High mobility group protein B1
  • HMG1
  • HMGB1
 view
P10412 Histone H1.4
  • H1-4
  • H1F4
  • HIST1H1E
 view
P16401 Histone H1.5
  • H1-5
  • H1F5
  • HIST1H1B
 view
Q14974 Importin subunit beta-1
  • KPNB1
  • NTF97
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025