Regulation of KIT signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PRKCAADPATPp-KIT (S741,746):PKC alphaKITp-KIT complexPTPN6:p-c-Kit complexSHP1SOCS1:p-KIT complexSOCS1SFKs:p-KIT complexAPS dimer:p-c-Kit:SFKs complexAPS dimerp-APS dimer:p-KIT complexCBLCBL:Grb2/p-APS:p-c-Kit complexGrb2:SOS:p-c-Kit/p-APS:p-c-Kit complexSOCS6SOCS6:p-c-Kit:sSCF dimer:p-c-KitLnkLNK:p-7Y-KIT:sSCF dimer:p-7Y-KIT
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P10721 Mast/stem cell growth factor receptor Kit
  • KIT
  • SCFR
view
P17252 Protein kinase C alpha type
  • PKCA
  • PRKACA
  • PRKCA
view
P22681 E3 ubiquitin-protein ligase CBL
  • CBL
  • CBL2
  • RNF55
view
P29350 Tyrosine-protein phosphatase non-receptor type 6
  • HCP
  • PTP1C
  • PTPN6
view
Q07889 Son of sevenless homolog 1
  • SOS1
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025