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MIRAGE
Glucagon signaling in metabolic regulation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GlucagonGlucagon:GCGRGCGRGs:GTPADCY5,6,8:G-alpha(s):GTPAdenylyl cyclase (pancreatic beta cell)GTPG-beta:G-gamma dimerG-protein with G(s) alpha:GDPGDPAdenylate cyclase (Mg2+ cofactor)Gs-activated adenylate cyclase
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 11 - 13 of 13 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q5JWF2 Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
  • GNAS
  • GNAS1
 view
Q8NFM4 Adenylate cyclase type 4
  • ADCY4
 view
Q9HAV0 Guanine nucleotide-binding protein subunit beta-4
  • GNB4
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025