2-LTR circle formation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
XRCC5:XRCC6Ku proteins bound to viral DNAviral PIC proteinsIN bound to sticky 3' ends of viral DNA in PICviral DNA:Ku proteins:XRCC4:DNA ligase IV complexXRCC4:LIG4IN (Integrase) (P04585) protein2-LTR form of circular viral DNA
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O75475 PC4 and SFRS1-interacting protein
  • DFS70
  • LEDGF
  • PSIP1
  • PSIP2
view
P12956 X-ray repair cross-complementing protein 6
  • G22P1
  • XRCC6
view
P13010 X-ray repair cross-complementing protein 5
  • G22P2
  • XRCC5
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025