Regulation of cholesterol biosynthesis by SREBP (SREBF)

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
CHOLSREBP1A,1C,2:SCAP:cholesterol:INSIGSREBP1A,1C,2:SCAPINSIGSAR1B:GTP:SEC23:SEC24SREBP1A,1C,2:SCAP:Cop II CoatSREBF1A,1C,2 cleaved by S2PSREBP1A,1C,2 dimerSREBP1A,1C,2:Importin beta-1SREBP1A,1C,2:Importin beta-1SREBP1A,1C,2:SCAP:INSIG:oxysterolINSIG:oxysterolSREBP1A,1C,2:SCAPSCAP tetramerSREBF1A,1C,2 cleaved by S1PKPNB1RAN:GTPImportin-beta:Ran GTP complexSREBP1A,1C,2 dimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025