Signaling by cytosolic FGFR1 fusion mutants

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
cytosolic FGFR1 fusion mutantscytosolic FGFR1 fusion mutant dimersTyrosine kinase inhibitors of FGFR1 fusion mutantsFGFR1 fusion mutant dimers:TKIsp-FGFR1 fusion mutant dimers:PIK3R1p-FGFR1 mutant fusions:PI3KPIK3CAATPpY177-BCR-p-FGFR1 fusion mutant dimerBCR-p-FGFR1 fusion mutant dimerADPpY177-BCR1-p-FGFR1 mutant:GRB2:GAB2GRB2:GAB2pY177-BCR-pY-FGFR1 mutant:GRB2:p-GAB2pY177-BCR-pY-FGFR1 mutant:GRB2:p-GAB1:PI3Kp-Y177-BCR-pY-FGFR1 mutant:GRB2:p-GAB2:PIK3R1STAT5p-STAT5STAT1, STAT3p-Y701-STAT1, p-Y705-STAT3cytosolic p-FGFR1 fusion mutant dimersPIK3R1PIP2PIP3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024