Signaling by activated point mutants of FGFR3

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
FGFR3 cysteine mutantsFGFR3 cysteine mutant dimersADPATPActivated FGFR3 cysteine mutantsFGFR3 point mutants with enhanced kinase activityFGFR3 point mutant dimers with enhanced kinase activityActivated FGFR3 mutants with enhanced kinase activityHSFGFR3c P250R mutant dimer bound to FGFFGFR3c P250RFGFR3c-binding FGFsActivated FGFR3c P250R mutant
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O43320 Fibroblast growth factor 16
  • FGF16
view
O76093 Fibroblast growth factor 18
  • FGF18
view
P22607 Fibroblast growth factor receptor 3
  • FGFR3
  • JTK4
view
P31371 Fibroblast growth factor 9
  • FGF9
view
Q9GZV9 Fibroblast growth factor 23
  • FGF23
  • HYPF
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024