Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
UDP-GlcNAcGlcNAcDOLDPUMPDOLPUDPN,N'-DCDOLDPMDCDDGDP-ManGDP(GlcNAc)2 (Man)2 (PP-Dol)1(GlcNAc)2 (Man)3 (PP-Dol)1glycan G00006glycan G00006DOLP-ManDOLPglycan G10595(GlcNAc)2 (Man)7 (PP-Dol)1(GlcNAc)2 (Man)8 (PP-Dol)1(GlcNAc)2 (Man)9 (PP-Dol)1DbGP(Glc)1 (GlcNAc)2 (Man)9 (PP-Dol)1glycan G10599glycan G00008
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025