Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ZFP36L1BRF1:mRNA ComplexmRNA Transcript Targeted by BRF1DCP2BRF1:mRNA Degradation ComplexExosome ComplexXRN1DCP1AATPADPPhosphorylated BRF1 (Ser92, Ser203):mRNA ComplexPhosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA ComplexYWHABPhosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 ComplexPhosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 7 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P31749 RAC-alpha serine/threonine-protein kinase
  • AKT1
  • PKB
  • RAC
view
Q13868 Exosome complex component RRP4
  • EXOSC2
  • RRP4
view
Q15024 Exosome complex component RRP42
  • EXOSC7
  • KIAA0116
  • RRP42
view
Q8IZH2 5'-3' exoribonuclease 1
  • SEP1
  • XRN1
view
Q96B26 Exosome complex component RRP43
  • EXOSC8
  • OIP2
  • RRP43
view
Q9NPI6 mRNA-decapping enzyme 1A
  • DCP1A
  • SMIF
view
Q9NQT4 Exosome complex component RRP46
  • CML28
  • EXOSC5
  • RRP46
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025