Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
MSH2MSH2:MSH6:ADPADPMSH6DNA containing mismatch or 1-2 base IDLMSH2:MSH6:ADP:DNA containing 1-2 base mismatchATPMSH2:MSH6:ATP:DNA containing 1-2 base mismatchPMS2MLH1:PMS2MLH1PCNA homotrimerMutLalpha:MutSalpha:ATP:PCNA:DNA with 1-2 base mismatchMutLalpha:MutSalpha:ATP:PCNA:DNA with 1-2 base mismatch and single strand incisionEXO1EXO1:MutLalpha:MutSalpha:ATP:PCNA:DNA with 1-2 base mismatch and single strand incisionRPA heterotrimerRPA:DNA containing single strand gapdATPDNA containing single strand nick (5' phosphate, 3' hydroxyl)dGTPdCTPTTPPPiAMPRepaired double-stranded DNA
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.0

Last updated: December 9, 2024