Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
dCTPDNA containing single strand nick (5' phosphate, 3' hydroxyl)dGTPRPA heterotrimerTTPdATPRPA:DNA containing single strand gapATPPPiAMPRepaired double-stranded DNAMSH3MutSbeta:ADPMSH2ADPDNA containing IDL of 2 or more basesMutSbeta:ADP:DNA containing IDL of 2 bases or moreMutSbeta:ATP:DNA containing IDL of 2 bases or moreMLH1:PMS2MutSbeta:MutSalpha:ATP:PCNA:DNA containing 1-2 base IDLPCNA homotrimerMutLalpha:MutSbeta:ATP:PCNA:DNA containing 1-2 base IDL and single strand incisionEXO1EXO1:MutLalpha:MutSbeta:ATP:PCNA:DNA containing 1-2 base IDL and single strand incision
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.2.1

Last updated: April 7, 2025