Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
AR:Androgensp-T774-PKN1:AR:Androgenp-T774-PKN1p-T774-PKN1:AR:Androgenp-T774-PKN1:AR:Androgen:NCOA2NCOA2KLK2,3 Gene:Nucleosome with H3K9me3p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3ADPATPp-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4CKDM4CO2p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H32OGCO2CH2OSUCCAKDM1Ap-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1Ap-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1Ap-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3KLK2,3 genesKLK2,KLK3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 21 - 27 of 27 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q8N257 Histone H2B type 3-B
  • H2BC26
  • H2BU1
  • HIST3H2BB
view
Q93079 Histone H2B type 1-H
  • H2BC9
  • H2BFJ
  • HIST1H2BH
view
Q99877 Histone H2B type 1-N
  • H2BC15
  • H2BFD
  • HIST1H2BN
view
Q99878 Histone H2A type 1-J
  • H2AC14
  • H2AFE
  • HIST1H2AJ
view
Q99879 Histone H2B type 1-M
  • H2BC14
  • H2BFE
  • HIST1H2BM
view
Q99880 Histone H2B type 1-L
  • H2BC13
  • H2BFC
  • HIST1H2BL
view
Q9H3R0 Lysine-specific demethylase 4C
  • GASC1
  • JHDM3C
  • JMJD2C
  • KDM4C
  • KIAA0780
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025