GLI proteins bind promoters of Hh responsive genes to promote transcription

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PTCH1 gene2p-GLI:PTCH1 gene2p-GLI1,2,32p-GLI:GLI1 geneGLI1 geneGLI1HHIP gene,PTCH2 gene,BOC gene2p-GLI1:HHIP gene,PTCH2 gene,BOC gene2p-GLI1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 3 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P08151 Zinc finger protein GLI1
  • GLI
  • GLI1
view
P10070 Zinc finger protein GLI2
  • GLI2
  • THP
view
P10071 Transcriptional activator GLI3
  • GLI3
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025