Negative regulation of MAPK pathway

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
RKTGPAQR3:inactive RAFsinactive RAFsRKIPp21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1p21RAS:GTP:activated RAF1 homo/heterodimerH2OPip21RAS:GTP:dephosphorylated RAF1 homo/heterodimerp21RAS:GTP:p-S621 RAF1 homo/heterodimerp-T,Y MAPK monomers and dimersMAPK monomers and dimersp-T,Y MAPK monomers and dimersMAPK monomers and dimersPiBRAPBRAP:KSR1:MARK3KSR1:MARK3p21 RAS:GTPp21 RAS:GTP:BRAPp21 RAS:GTP:ub-BRAPUbPTPN7PTPN7:p-T,Y-MAPK dimersp-ERK dimerPTPN7:p-T-MAPK dimersP-MAPK12PTPN3:p-T183,Y185-MAPK12PTPN3MAPK12ADPATPp-S459 PTPN3:p-T183,Y185-MAPK12
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.2.1

Last updated: April 7, 2025