Regulation of TP53 Activity through Phosphorylation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
DYRK2p-T106,S442-DYRK2ADPATPp-S15,S20-TP53 Tetramerp-S15,S20,S46-TP53 TetramerPolyUb-DYRK2UbTP53INP1:p-HIPK2:PIN1:p-S15,S20-TP53p-HIPK2:PIN1TP53INP1MYAKTP53 Tetramer:HIPK1TP53 TetramerSTK11TP53 Tetramer:STK11:NUAK1ARK5TP53 Tetramer:STK11:p-T211-NUAK1p-T211-NUAK1p-S15,S392-TP53 Tetramerp-S15,S20,S392-TP53 Tetramerp-S315-TP53 TetramerNOC2L:p-S15,S20-TP53NIRAURKBAURKB:NOC2L:p-S15,S20-TP53AURKB:NOC2L:p-S15,S20,S269,T284-TP53p-S15,S33,S46-TP53 Tetramerp-T55-TP53 Tetramerp-S37-TP53 Tetramerp-S15-TP53 TetramerCK2CK2:FACTFACT complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 50 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O00268 Transcription initiation factor TFIID subunit 4
  • TAF2C
  • TAF2C1
  • TAF4
  • TAF4A
  • TAFII130
  • TAFII135
view
O14757 Serine/threonine-protein kinase Chk1
  • CHEK1
  • CHK1
view
O60934 Nibrin
  • NBN
  • NBS
  • NBS1
  • P95
view
O75943 Cell cycle checkpoint protein RAD17
  • R24L
  • RAD17
view
O96017 Serine/threonine-protein kinase Chk2
  • CDS1
  • CHEK2
  • CHK2
  • RAD53
view
P04637 Cellular tumor antigen p53
  • P53
  • TP53
view
P15927 Replication protein A 32 kDa subunit
  • REPA2
  • RPA2
  • RPA32
  • RPA34
view
P19784 Casein kinase II subunit alpha'
  • CK2A2
  • CSNK2A2
view
P20226 TATA-box-binding protein
  • GTF2D1
  • TBP
  • TF2D
  • TFIID
view
P27694 Replication protein A 70 kDa DNA-binding subunit
  • REPA1
  • RPA1
  • RPA70
view
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.2.1

Last updated: April 7, 2025