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MIRAGE
Negative regulation of MET activity

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
H2OPiHGF:p-4Y-MET dimerHGF:p-3Y-MET dimerHGF:p-2Y-MET dimerCBL:GRB2,CBLHGF:p-4Y-MET dimer:GRB2:CBL,(HGF:p-Y1003,4Y-MET dimer:CBL)HGF:p-4Y-MET dimer,(HGF:p-Y1003,4Y-METdimer)ADPATPHGF:p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:p-Y1003,4Y-MET dimer:p-Y-CBL)HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-MET dimer:p-Y-CBL)UbHGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillinCIN85:endophilinLRIG1MET:LRIG1METMET:Ub-LRIG1HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin,(MET:Ub-LRIG1)HGF:MonoUb-K,p-4Y-MET dimer:GRB2:p-Y-CBL,(HGF:MonoUb-K,p-Y1003,4Y-METdimer:p-Y-CBL):CIN85:endophillin:EPS15:HGS:STAM,(MET:Ub-LRIG1:EPS15:HGS:STAM)EPS15:HGS:STAM
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 11 - 16 of 16 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
P62987 Ubiquitin-ribosomal protein eL40 fusion protein
  • UBA52
  • UBCEP2
 view
Q12913 Receptor-type tyrosine-protein phosphatase eta
  • DEP1
  • PTPRJ
 view
Q96B97 SH3 domain-containing kinase-binding protein 1
  • CIN85
  • SH3KBP1
 view
Q96JA1 Leucine-rich repeats and immunoglobulin-like domains protein 1
  • LIG1
  • LRIG1
 view
Q99961 Endophilin-A2
  • CNSA1
  • SH3D2B
  • SH3GL1
 view
Q99963 Endophilin-A3
  • CNSA3
  • SH3D2C
  • SH3GL3
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025