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Stabilization of p53

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPp-S15-TP53 TetramerTP53 TetramerADPp-S15,S20-TP53 Tetramerp-MDM2p-5S,T-MDM2p-S166,S188-MDM2:MDM4p-S166,S188-MDM2:p-S403-MDM4p-S166,S188-MDM2,MDM4p-S166,S188-MDM2 dimer, p-S166,S188-MDM2:MDM4UbPolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4p-S166,S188-MDM2:p-S346,S367,S403-MDM4p-S166,S188-MDM2 dimer, p-S166,S188-MDM2,MDM4:TP53PolyUb-TP53 TetramerPolyUb-TP53 Tetramer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025