Assembly of active LPL and LIPC lipase complexes

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HSPGHSPG:LPL dimerLPL dimerGPIHBP1GPIHBP1:HSPG:LPL dimerANGPTL8ANGPTL3:ANGPTL8ANGPTL3LPLCREB-HCR3L3_HUMANCR3L3_HUMANCR3L3_HUMANAPOA4,APOA5,APOC2,CIDEC,FGF21 genesAPOA4,APOA5,APOC2,CIDEC,FGF21LMF1,2LIPC dimer:LMF1,2LIPC dimerLIPC dimerLIPC dimer:heparinHeparinsH2ODAGTAGsFAs
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 11 - 16 of 16 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1
  • GPIHBP1
  • HBP1
view
Q92824 Proprotein convertase subtilisin/kexin type 5
  • PC5
  • PC6
  • PCSK5
view
Q96S06 Lipase maturation factor 1
  • C16orf26
  • LMF1
  • TMEM112
view
Q9BU23 Lipase maturation factor 2
  • LMF2
  • TMEM112B
  • TMEM153
view
Q9BY76 Angiopoietin-related protein 4
  • ANGPTL4
  • ARP4
  • HFARP
  • PGAR
view
Q9Y5C1 Angiopoietin-related protein 3
  • ANGPT5
  • ANGPTL3
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025