Loss of MECP2 binding ability to the NCoR/SMRT complex

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
NCoR/SMRT complexMECP2 mutants P302R,K304E,K305R,R306C,(R306H)
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O15379 Histone deacetylase 3
  • HDAC3
view
O60907 F-box-like/WD repeat-containing protein TBL1X
  • TBL1
  • TBL1X
view
O75376 Nuclear receptor corepressor 1
  • KIAA1047
  • NCOR1
view
Q13227 G protein pathway suppressor 2
  • GPS2
view
Q9Y618 Nuclear receptor corepressor 2
  • CTG26
  • NCOR2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025