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MIRAGE
Erythropoietin activates Phospholipase C gamma (PLCG)

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:PLCG1,2PLC gamma1,2ATPEPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-PLCG1,2ADPPIP2DAGH2OIP3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P01588 Erythropoietin
  • EPO
 view
P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
  • PLC1
  • PLCG1
 view
P19235 Erythropoietin receptor
  • EPOR
 view
Q9Y4H2 Insulin receptor substrate 2
  • IRS2
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025