Chaperone Mediated Autophagy

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Substrates for chaperone mediated autophagyHSPA8 bound autophagic substratesHSPA8HSPA8:Substrate:LAMP2aLAMP2Substrate:LAMP2aHSP90AA1, HSP90AB1Substrate:LAMP2a:HSP90LAMP2a multimer complexLAMP2a multimer complex:GFAPGFAPHSPA8HSPA8:LAMP2a multimeric complexHSPA8:LAMP2a multimeric complexLAMP2a multimer complex:GFAPHSPA8:Substrates for CMAEEF1A1p-GFAP:EEF1A1p-GFAPEEF1A1:GTPGTPEEF1A1:GTPp-GFAP:GFAP:LAMP2a multimerp-GFAP:GFAPLAMP2a multimer complexHSPA8:LAMP2a multimersHSPA8:LAMP2a multimersLAMP2a:HSP90
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 16 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O60664 Perilipin-3
  • M6PRBP1
  • PLIN3
  • TIP47
view
O95613 Pericentrin
  • KIAA0402
  • PCNT
  • PCNT2
view
P07900 Heat shock protein HSP 90-alpha
  • HSP90A
  • HSP90AA1
  • HSPC1
  • HSPCA
view
P07998 Ribonuclease pancreatic
  • RIB1
  • RNASE1
  • RNS1
view
P08238 Heat shock protein HSP 90-beta
  • HSP90AB1
  • HSP90B
  • HSPC2
  • HSPC3
  • HSPCB
view
P11142 Heat shock cognate 71 kDa protein
  • HSC70
  • HSP73
  • HSPA10
  • HSPA8
view
P13473 Lysosome-associated membrane glycoprotein 2
  • LAMP2
view
P13569 Cystic fibrosis transmembrane conductance regulator
  • ABCC7
  • CFTR
view
P14136 Glial fibrillary acidic protein
  • GFAP
view
P62979 Ubiquitin-ribosomal protein eS31 fusion protein
  • RPS27A
  • UBA80
  • UBCEP1
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025