Sealing of the nuclear envelope (NE) by ESCRT-III

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
CHMP7LEMD2:CHMP7LEM2CHMP6LEMD2:ESCRT-III:IST1IST1CHMP4CCHMP4BCHMP2ACHMP4ACHMP2BCHMP3LEM2D:ESCRT-III:IST1:CC2D1BCC2D1BLEM2D:ESCRT-III:IST1:CC2D1B:SPASTSPASTH2OPiMicrotubuleADPATPalpha-beta tubulin dimerVPS4ALEM2D:ESCRT-III:IST1:CC2D1B:SPAST:VPS4AH+
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 19 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
A6NNZ2 Tubulin beta 8B
  • TUBB8B
view
P04350 Tubulin beta-4A chain
  • TUBB4
  • TUBB4A
  • TUBB5
view
P68363 Tubulin alpha-1B chain
  • TUBA1B
view
P68366 Tubulin alpha-4A chain
  • TUBA1
  • TUBA4A
view
P68371 Tubulin beta-4B chain
  • TUBB2C
  • TUBB4B
view
Q13509 Tubulin beta-3 chain
  • TUBB3
  • TUBB4
view
Q13885 Tubulin beta-2A chain
  • TUBB2
  • TUBB2A
view
Q5T0F9 Coiled-coil and C2 domain-containing protein 1B
  • CC2D1B
  • KIAA1836
  • LGD1
view
Q71U36 Tubulin alpha-1A chain
  • TUBA1A
  • TUBA3
view
Q8NC56 LEM domain-containing protein 2
  • LEMD2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025