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Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function

Summary

Species

Homo sapiens

Reactome

R-HSA-9704331

PubChem

R-HSA-9704331

Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.

SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018

Displaying entries **1 - 10** of 15 in total

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UniProt ID	Protein Name	Gene Symbol	Pathway Viewer
O15315	DNA repair protein RAD51 homolog 2	RAD51B RAD51L1 REC2	view
O43502	DNA repair protein RAD51 homolog 3	RAD51C RAD51L2	view
O60934	Nibrin	NBN NBS NBS1 P95	view
P38398	Breast cancer type 1 susceptibility protein	BRCA1 RNF53	view
P49959	Double-strand break repair protein MRE11	HNGS1 MRE11 MRE11A	view
P51587	Breast cancer type 2 susceptibility protein	BRCA2 FACD FANCD1	view
P54132	RecQ-like DNA helicase BLM	BLM RECQ2 RECQL3	view
Q13315	Serine-protein kinase ATM	ATM	view
Q13472	DNA topoisomerase 3-alpha	TOP3 TOP3A	view
Q86YC2	Partner and localizer of BRCA2	FANCN PALB2	view

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