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MIRAGE
FLT3 signaling through SRC family kinases

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Active FLT3Active FLT3:FYNFYNHCKActive FLT3:HCKactive FLT3:LCKLCKactive FLT3:SYKSYK
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P08631 Tyrosine-protein kinase HCK
  • HCK
 view
P36888 Receptor-type tyrosine-protein kinase FLT3
  • CD135
  • FLK2
  • FLT3
  • STK1
 view
P43405 Tyrosine-protein kinase SYK
  • SYK
 view
P49771 Fms-related tyrosine kinase 3 ligand
  • FLT3LG
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025