Heme signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
MetHbApoHbFeHMLDL,HDLoxidized LDL,HDLhemeMD2Hemes:LY96HemesTLR4:Hemes:LY96TLR4CLEC1B dimerCLEC1B dimer:HemesPGRMC2PGRMC2:HemesHemesPGRMC2:HemesPGRMC2HemesBACH1:HemesMAFKBACH1:MAFKXPO1:BACH1:HemesXPO1XPO1:BACH1:HemesPPARGC1A genePGC1ANPAS2 geneNPAS2ferrohemoglobinhydroxideH2O2hydroxylBACH1HMOX1 geneHMOX1 dimerNR1D1NR1D1:heme:Corepressors:ARNTL geneNCOR1HDAC3ferriheme bARNTL geneCLOCK geneNR1D1:heme:Corepressors:CLOCK geneNR1D1:heme:Corepressors:NPAS2 geneNR1D1 geneNR1D1:heme:Corepressors:NR1D1 geneNR1D1:heme:Corepressors:PPARGC1A geneARNTLCLOCK
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying 1 entry
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000137 Q9P126 C-type lectin domain family 1 member B view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025