M-decay: degradation of maternal mRNAs by maternally stored factors

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
mRNA regulated by ZFP36L2CCR4-NOT(CNOT6L):ZFP36L2:mRNACCR4-NOT Complex (CNOT6L)ZFP36L2H2OCCR4-NOT(CNOT6L):ZFP36L2:deadenylated mRNAAMPCCR4-NOT Complex (CNOT7)CCR4-NOT:BTG4:PABPN1L:mRNPPABPN1LBTG4mRNP regulated by BTG4CCR4-NOT:BTG4:PABPN1L:deadenylated mRNPmaternal mRNA:lncRNAmaternal endosiRNAAGO2AGO2:maternal endosiRNAmaternal mRNA 3' fragmentmaternal mRNAmaternal mRNA 5' fragment
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 11 - 17 of 17 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q96LI5 CCR4-NOT transcription complex subunit 6-like
  • CCR4B
  • CNOT6L
view
Q9C0C2 182 kDa tankyrase-1-binding protein
  • KIAA1741
  • TAB182
  • TNKS1BP1
view
Q9H9A5 CCR4-NOT transcription complex subunit 10
  • CNOT10
view
Q9NZN8 CCR4-NOT transcription complex subunit 2
  • CDC36
  • CNOT2
  • NOT2
view
Q9UKV8 Protein argonaute-2
  • AGO2
  • EIF2C2
view
Q9UKZ1 CCR4-NOT transcription complex subunit 11
  • C2orf29
  • CNOT11
view
Q9UPY3 Endoribonuclease Dicer
  • DICER
  • DICER1
  • HERNA
  • KIAA0928
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025