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MIRAGE
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
p21 geneMITF-M dimer:CDKN1A geneMITF-M dimerMITF-M dimer:MET geneMET geneMITF-M dimer:CDK2 geneCDK2 geneMITF-M dimer:CCND1 geneCCND1 geneHINT1 dimerHINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 geneSIN3AHDAC1TCF/LEF:CTNNB1:CCND1 geneMITF-M dimer:CDKN2A geneCDKN2A genePLK1 GeneMITF-M dimer:PLK1 geneTBX2 geneMITF-M:TBX2 geneTBX2p21METCDK2MITF-M dimer:CCNB1 geneCCNB1 GeneCCNB1TCF/LEF:CTNNB1CCND1MTS1PLK1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025