Mitochondrial unfolded protein response (UPRmt)

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HSDJDNJA1_HUMANROSHSF1HSPA1A,B:ox-C149,C150-DNAJA1HSF1:HSPA1A,BADPATPp-S326-HSF1 trimerATF5ATF5ATF5HSPA9 geneATF5:HSF1 trimer:HSPA9 geneHSPA9ATF5:HSF1 trimer:HSPD1 gene:HSPE1 geneHSPE1 geneHSPD1 geneHSPD1HSPE1LONP1 geneLONP1DEFA5 geneDEFA5PKBPKBESR1 dimerp-S167-ESR1 dimerp-S167-ESR1 dimerHTRA2 geneOMINRF1 geneNRF1FOXO3_HUMAN2'-O-acetyl-ADP-riboseH2OFOXO3_HUMANNADFOXO3MnSODSOD2CAT geneCAT
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 15 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O43524 Forkhead box protein O3
  • FKHRL1
  • FOXO3
  • FOXO3A
view
P03372 Estrogen receptor
  • ESR
  • ESR1
  • NR3A1
view
P04040 Catalase
  • CAT
view
P04179 Superoxide dismutase [Mn], mitochondrial
  • SOD2
view
P0DMV8 Heat shock 70 kDa protein 1A
  • HSP72
  • HSPA1
  • HSPA1A
  • HSX70
view
P0DMV9 Heat shock 70 kDa protein 1B
  • HSP72
  • HSPA1B
view
P10809 60 kDa heat shock protein, mitochondrial
  • HSP60
  • HSPD1
view
P31749 RAC-alpha serine/threonine-protein kinase
  • AKT1
  • PKB
  • RAC
view
P36776 Lon protease homolog, mitochondrial
  • LONP1
  • PRSS15
view
P38646 Stress-70 protein, mitochondrial
  • GRP75
  • HSPA9
  • HSPA9B
  • mt-HSP70
view
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.2.1

Last updated: April 7, 2025