Signaling by ERBB2

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
NRG1/2NRG1/2:ERBB3Q61526ERBB2:ERBIN:HSP90:CDC37ERBB2 heterodimersCDC37ErbinLigand-Activated EGFR/ERBB3/ERBB4HSP90ATPp-Y877-ERBB2 heterodimersADPAutophosphorylated p-Y877-ERBB2 heterodimersp-6Y-ERBB2 heterodimers
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 11 - 13 of 13 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q61526 Receptor tyrosine-protein kinase erbB-3
  • Erbb3
view
Q61527 Receptor tyrosine-protein kinase erbB-4
  • Erbb4
  • Mer4
view
Q80TH2 Erbin
  • Erbb2ip
  • Erbin
  • Kiaa1225
  • Lap2
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025