Regulation of cholesterol biosynthesis by SREBP (SREBF)

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
SREBP1A,1C,2:SCAPSCAP tetramerSREBF1A,1C,2 cleaved by S1PSREBF1A,1C,2 cleaved by S2PSREBP1A,1C,2 dimerKpnb1SREBP1A,1C,2:Importin beta-1SREBP1A,1C,2:Importin beta-1Importin-beta:Ran GTP complexRAN:GTPSREBP1A,1C,2 dimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025