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MIRAGE
Signaling by PDGF

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PDGF precursor dimers (AA, BB, A/B, CC, DD)PDGF precursor dimers (AA, BB, A/B, CC, DD)proPDGF-AA dimerPdgfaactive PDGF-AA dimerproPDGF-BB dimerPdgfbactive PDGF-BB dimerproPDGF-AB dimerPDGF A/B heterodimerNovel PDGF precursor dimers (CC, DD)Novel PDGF precursor dimers (CC, DD)Active PDGF dimers (CC, DD)Cleaved novel PDGF fragmentsExtracellular matrix ligandsPDGF A and B chains:ECM complexPDGF A and B chains with retention motifActive PDGF dimers (AA, AB, BB)PDGF:PDGF receptor dimerPDGFRA, PDGFRBPDGF beta receptor:PDGF chain B homodimerADPATPPhospho PDGF beta receptor: PDGF chain B homodimerPDGF alpha receptor: PDGF dimersPhospho PDGF alpha receptor:PDGF dimersPDGF alpha/beta:PDGF AB and BB dimersPhospho PDGF alpha-beta dimer:PDGF AB or BB dimersp-PDGFRB homo and heterodimersPip-PDGFRB homo and heterodimers dephosphorylated at Y1021H2OPDGFR:type I PDGFR-binding TKIstype I PDGFR-binding tyrosine kinase inhibitorstype II PDGFR-binding tyrosine kinase inhibitorsPDGFR:type II PDGFR-binding TKIs
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying entries 1 - 10 of 25 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
A6H584 Collagen alpha-5(VI) chain
  • Col29a1
  • Col6a5
  • Gm7455
 view
E9PWQ3 Collagen, type VI, alpha 3
  • Col6a3
 view
P02463 Collagen alpha-1(IV) chain
  • Col4a1
 view
P05622 Platelet-derived growth factor receptor beta
  • Pdgfr
  • Pdgfr1
  • Pdgfrb
 view
P08122 Collagen alpha-2(IV) chain
  • Col4a2
 view
P10923 Osteopontin
  • Eta-1
  • Op
  • Spp-1
  • Spp1
 view
P11214 Tissue-type plasminogen activator
  • Plat
 view
P20033 Platelet-derived growth factor subunit A
  • Pdgfa
 view
P20918 Plasminogen
  • Plg
 view
P23188 Furin
  • Fur
  • Furin
  • Pcsk3
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025