HS-GAG degradation

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HS/HPIN-PGsHS/HPIN-PGsH2OHeparan sulfate chain(1)HS core proteinsHpse2HPSE2:HS/HPIN-PGsHeparan sulfate chain(2)L-Iduronic acidHeparan sulfate chain(3)SO4(2-)Ac-CoAHeparan sulfate chain(4)CoA-SHGlcNAcHeparan sulfate chain(5)Heparan sulfate chain(6)Heparan sulfate chain(7)Heparan chain(1)Heparan chain(2)CS/HS precursorGlcAlinker chain(2)D-xyloseGal
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 11 - 19 of 19 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q08890 Iduronate 2-sulfatase
  • Ids
view
Q64519 Syndecan-3
  • Kiaa0468
  • Sdc3
view
Q6YGZ1 Heparanase
  • Hpa
  • Hpse
view
Q8BKV1 Glypican-2
  • Gpc2
view
Q8CAL5 Glypican-5
  • Gpc5
view
Q8CFZ4 Glypican-3
  • Gpc3
view
Q8VC60 Beta-galactosidase-1-like protein
  • Glb1l
view
Q9EQ08 Heparan N-sulfatase
  • Sgsh
view
Q9QZF2 Glypican-1
  • Gpc1
view
Displaying all 2 entries
GlyTouCan ID KEGG GLYCAN ChEBI Pathway Viewer
G01550VL
view
G09546QO
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025