eNOS activation

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Calmodulin:CalciumeNOS:Caveolin-1:CaMeNOS:Caveolin-1P07901eNOS:Caveolin-1:CaM:HSP90eNOS:CaM:HSP90Cav1eNOS:CaM:HSP90:p-AKT1P31750p-S1177-eNOS:CaM:HSP90:p-AKT1ADPATPH+BH4p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4TPNO2L-ArgNOTPNHH2OL-CitPALM-CoACoA-SHP70313P70313palmitoylated, myristoylated eNOS dimerq-BH2sepiapterinp-S1177-eNOS:CaM:HSP90:p-AKT1:BH2ADMADMAO2.-myristoylated eNOS dimerPALMmyristoylated eNOS dimerCYBG(Fe3+) dimerNO3-CYGB(Fe2+) dimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 7 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P07901 Heat shock protein HSP 90-alpha
  • Hsp86
  • Hsp86-1
  • Hsp90aa1
  • Hspca
view
P31750 RAC-alpha serine/threonine-protein kinase
  • Akt
  • Akt1
  • Rac
view
P70313 Nitric oxide synthase 3
  • Ecnos
  • Nos3
view
P97823 Acyl-protein thioesterase 1
  • Apt1
  • Lypla1
  • Pla1a
view
Q64105 Sepiapterin reductase
  • Spr
view
Q9CWS0 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
  • Ddah1
view
Q9CX80 Cytoglobin
  • Cygb
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025