DEx/H-box helicases activate type I IFN and inflammatory cytokines production

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
NFKB1(1-433), NFKB2(1-454):RELANFKB1(1-433), NFKB2(1-454):RELADHX36DHX36:CpGUnmethylated CpG DNADHX9DHX9:CpGDHX9/DHX36:CpGDHX9/DHX36:CpG:MyD88Myd88p-2S-IRF7:p-2S-IRF72xp-S477,S479-IRF7
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O70133 ATP-dependent RNA helicase A
  • Ddx9
  • Dhx9
view
P25799 Nuclear factor NF-kappa-B p105 subunit
  • Nfkb1
view
Q04207 Transcription factor p65
  • Nfkb3
  • Rela
view
Q8VHK9 ATP-dependent DNA/RNA helicase DHX36
  • Ddx36
  • Dhx36
  • Kiaa1488
  • Mlel1
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025