Signaling by ROBO receptors

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GPC1:HSPGSLIT2,SLIT2 cleavage fragments:GPC1:HSPGSlit2SLIT2,(SLIT3)SLIT2,(SLIT3):Keratan sulfateKeratan sulfateROBO1,ROBO2:Keratan sulfateRobo1ROBO1:SLIT2PFNSLIT2:ROBO1:Ena/VASP:PFNSLIT2:ROBO1:Ena/VASP proteinsCXCR4:CXCL12CXCL12:CXCR4:ROBO1:SLIT2
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 7 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O89026 Roundabout homolog 1
  • Dutt1
  • Robo1
view
P62962 Profilin-1
  • Pfn1
view
P70658 C-X-C chemokine receptor type 4
  • Cmkar4
  • Cxcr4
  • Lestr
  • Sdf1r
view
Q03173 Protein enabled homolog
  • Enah
  • Mena
  • Ndpp1
view
Q9QZF2 Glypican-1
  • Gpc1
view
Q9R1B9 Slit homolog 2 protein
  • Slit2
view
Q9WVB4 Slit homolog 3 protein
  • Slit3
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025