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MIRAGE
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
P23950BRF1:mRNA ComplexmRNA Transcript Targeted by BRF1Exosome ComplexBRF1:mRNA Degradation ComplexDCP2Dcp1aXrn1ATPADPPhosphorylated BRF1 (Ser92, Ser203):mRNA ComplexPhosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA ComplexPhosphorylated BRF1 (Ser92, Ser203):mRNA:14-3-3 ComplexYwhabPhosphorylated BRF1 (Ser54, Ser92, Ser203):mRNA:14-3-3 Complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P31750 RAC-alpha serine/threonine-protein kinase
  • Akt
  • Akt1
  • Rac
 view
P97789 5'-3' exoribonuclease 1
  • Dhm2
  • Exo
  • Sep1
  • Xrn1
 view
Q91YD3 mRNA-decapping enzyme 1A
  • Dcp1a
  • Mitc1
  • Smif
 view
Q9CSH3 Exosome complex exonuclease RRP44
  • Dis3
  • Kiaa1008
  • Rrp44
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025